Rejection
What is rejection?
Rejection is the immune system's normal and expected reaction to
foreign matter in the body, including the transplanted kidney. Although your
risk for rejection decreases over time, it never goes away. The risk is always
there, which is why you must follow your medical treatment plan closely.
Approximately 90% of rejection episodes are successfully treated.
What can I do to help prevent rejection?
The following suggestions offer some things you can do to keep your new kidney healthy and lessen your chances of rejection. However, remember that your
physician and the transplant team are your best sources of information for your
particular medical treatment plan.
- Take your medications exactly as prescribed. Many medications must be taken at the same time each day. Never discontinue a medication or
change the dosage unless instructed to do so by the transplant team. If you
have trouble remembering whether you've taken a medication, use a
medication planner or pillbox.
- Visits to your local lab are scheduled at regular intervals. Your
transplant team uses the results of these tests to monitor the levels of
medications in your blood, as well as to check for infections, signs of rejection, and other medical conditions.
- Maintain proper nutrition to stay healthy. Regular exercise is also
important to maintaining good health.
- Stop smoking. Smoking constricts your blood vessels and can have damaging
effects on your transplanted kidney.
- Avoid drinking alcohol, including beer and wine. Many medications do not
mix with alcohol.
- Illicit drugs, including marijuana, are never acceptable for transplant
recipients.
What can I do to prevent infections?
- wash your hands, especially before eating anything
- keep your hands away from your face and mouth
- avoid people who have colds or infections
- ask visitors not to come if they are ill
- brush your teeth twice daily and visit your dentist twice each year
- avoid handling animal waste
What are some of the signs of rejection?
Memorize the signs of rejection and monitor yourself for them every day:
- fever
- shortness of breath
- lightheadedness
- cough
- prolonged nausea, vomiting, or diarrhea
- inability to take medications (due to vomiting, for example)
- skin rash
- vaginal discharge or itching
- pain or a burning feeling upon urination
- tenderness, redness, or swelling at the incision site
- decrease in urine output
- strong odor to the urine
- blood in the urine
- fluid retention or weight gain of 2 lbs. in 24 hours
What should I do if I notice any of the signs of rejection?
Immediately call your local VA renal physician or transplant nurse
coordinator for instructions. Your local VAMC team may consult with the VA Iowa City Health Care System transplant team. Your symptoms will be evaluated and an appropriate treatment
plan will be determined.
What happens if my new kidney fails?
Even if you follow every suggestion listed above, rejection is still
possible. Most transplant recipients will experience some kind of rejection, but
that does not necessarily mean that they will lose their new kidney. If you do
lose your new kidney, you will have to return to dialysis. At that point you may
be asked to consider if you would like to undergo another kidney transplant,
provided the transplant team has given their approval.
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